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30 Revolutionary Medical Trivia Questions and Answers

Reviewed by Stefanie Zaldarriaga, Author·Updated Oct 2025·4 min read
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  1. 1In what year did the World Health Assembly declare smallpox eradicated worldwide?

  2. 2Who performed the first successful vaccination and in what year?

  3. 3Who discovered the ABO blood groups, making safe transfusion possible?

  4. 4Which discovery in 1928 revolutionized treatment of bacterial infections?

  5. 5What is the leading global cause of death today?

  6. 6What is the most abundant protein in the human body?

  7. 7What is the largest organ of the human body?

  8. 8What is the longest bone in the human body?

  9. 9Which blood type is the universal red cell donor?

  10. 10Which blood type is the universal red cell recipient?

  11. 11How many bones are in a typical adult human skeleton?

  12. 12Which solid organ uniquely regenerates to restore its original mass?

  13. 13Who first isolated insulin for diabetes treatment and when?

  14. 14What were the first widely used systemic antibacterial drugs before penicillin?

  15. 15For how long should you scrub when washing hands with soap and water?

  16. 16Deficiency of which vitamin causes scurvy?

  17. 17Deficiency of which vitamin causes rickets in children?

  18. 18What is the most common nutritional cause of anaemia worldwide?

  19. 19What is the heart’s natural pacemaker?

  20. 20What is the smallest bone in the human body?

  21. 21Tenderness at which point is a classic sign of appendicitis?

  22. 22Which imaging modality does not use ionizing radiation to make images?

  23. 23Do antibiotics treat viral infections like colds or flu?

  24. 24What are the two most common causes of peptic ulcers?

  25. 25What temperature range is generally considered normal for adult body temperature?

  26. 26When and where was the first successful human organ transplant performed?

  27. 27What infection is the necessary cause of nearly all cervical cancers?

  28. 28How much folic acid should people capable of pregnancy get daily to help prevent neural tube defects?

  29. 29Which hormone from the pineal gland helps regulate the sleep–wake cycle?

  30. 30What cancer currently causes the most deaths worldwide?

Answer Key

  1. 1. 1980
  2. 2. Edward Jenner, 1796
  3. 3. Karl Landsteiner
  4. 4. Penicillin
  5. 5. Cardiovascular disease
  6. 6. Collagen
  7. 7. Skin
  8. 8. Femur
  9. 9. O negative
  10. 10. AB positive
  11. 11. 206
  12. 12. Liver
  13. 13. Frederick Banting and Charles Best, 1921
  14. 14. Sulfonamides (sulfa drugs)<br/Discovered in the 1930s (e.g., Prontosil), they became widely used by the 1940s.
  15. 15. At least 20 seconds
  16. 16. Vitamin C (ascorbic acid)
  17. 17. Vitamin D
  18. 18. Iron deficiency
  19. 19. The sinoatrial (SA) node
  20. 20. Stapes (in the middle ear)
  21. 21. McBurney’s point (right lower quadrant)
  22. 22. MRI
  23. 23. No
  24. 24. Helicobacter pylori infection and NSAID use
  25. 25. About 97–99 °F (36.1–37.2 °C)
  26. 26. Kidney transplant, Boston, December 23, 1954
  27. 27. Persistent infection with high-risk human papillomavirus (HPV)
  28. 28. 400 micrograms (mcg)
  29. 29. Melatonin
  30. 30. Lung cancer

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